I just discovered that my label printer apparently disconnects from USB while printing. So for every label I print, there's a disconnect event, then a re-enumeration event.
Probably due to power draw. A lot of modern label printers use thermal inks and heating the heads essentially leaves insufficient current to maintain other connections. I had a similar problem using a thermal printer on a raspberry pi.
@foone
Whoa, that would blow up so badly on qubes, where you have to pass a usb device to the VM where you're doing something with it, and disappearing device would need to be reconnected by you.